Assay Detail
Physicochemical
CHEMBL3756633
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Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by ELISA reader analysis
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel 7-O-lipophilic substituted baicalein derivatives as potential anticancer agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 4.68 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.08 |
| CHEMBL3753569 | — | — | 1 | 4.89 |
| CHEMBL8260 | BAICALEIN | 2.0 | 1 | 4.76 |
| CHEMBL3753737 | — | — | 1 | 4.67 |
| CHEMBL153 | TROLOX | — | 1 | 4.64 |
| CHEMBL3752049 | — | — | 1 | 4.63 |
| CHEMBL3753264 | — | — | 1 | 4.63 |
| CHEMBL1782451 | — | — | 1 | 4.62 |
| CHEMBL1782454 | — | — | 1 | 4.61 |
| CHEMBL3754716 | — | — | 1 | 4.61 |
| CHEMBL196 | ASCORBIC ACID | 4.0 | 1 | 4.56 |
| CHEMBL296800 | — | — | 1 | 4.55 |
| CHEMBL3753019 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | IC50 | = | 8410.0 | nM | 5.08 |
| CHEMBL3753569 | — | IC50 | = | 12910.0 | nM | 4.89 |
| CHEMBL8260 | BAICALEIN | IC50 | = | 17180.0 | nM | 4.76 |
| CHEMBL3753737 | — | IC50 | = | 21530.0 | nM | 4.67 |
| CHEMBL153 | TROLOX | IC50 | = | 22700.0 | nM | 4.64 |
| CHEMBL3752049 | — | IC50 | = | 23590.0 | nM | 4.63 |
| CHEMBL3753264 | — | IC50 | = | 23510.0 | nM | 4.63 |
| CHEMBL1782451 | — | IC50 | = | 23970.0 | nM | 4.62 |
| CHEMBL1782454 | — | IC50 | = | 24340.0 | nM | 4.61 |
| CHEMBL3754716 | — | IC50 | = | 24590.0 | nM | 4.61 |
| CHEMBL196 | ASCORBIC ACID | IC50 | = | 27300.0 | nM | 4.56 |
| CHEMBL296800 | — | IC50 | = | 28400.0 | nM | 4.55 |
| CHEMBL3753019 | — | IC50 | = | 28580.0 | nM | 4.54 |