Assay Detail

CHEMBL3760554

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Functional

Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Open DB target context

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NON-PROTEIN TARGET (CHEMBL3879801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HCT-116
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Phomanolides A and B from the Fungus Phoma sp.: Meroterpenoids Derived from a Putative Tropolonic Sesquiterpene via Hetero-Diels-Alder Reactions.

Zhang J, Liu L, Wang B, Zhang Y, Wang L, Liu X, Che Y.
J Nat Prod (2015) 78 : 3058 -3066
PubMed 26651221 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.51	7.51

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3758224	—	—	1	7.51

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3758224	—	IC50	=	31.2	nM	7.51