Assay Detail
ADMET
CHEMBL3760817
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Antiproliferative activity against human WI38 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 4.64 | 4.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3758634 | — | — | 1 | 4.76 |
| CHEMBL3759102 | — | — | 1 | 4.70 |
| CHEMBL3759201 | — | — | 1 | 4.58 |
| CHEMBL3759797 | — | — | 1 | 4.52 |
| CHEMBL3758988 | — | — | 1 | - |
| CHEMBL3759939 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3758634 | — | EC50 | = | 17500.0 | nM | 4.76 |
| CHEMBL3759102 | — | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL3759201 | — | EC50 | = | 26600.0 | nM | 4.58 |
| CHEMBL3759797 | — | EC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL3758988 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL3759939 | — | EC50 | > | 50000.0 | nM | - |