Assay Detail
Binding
CHEMBL3762571
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced twitches
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multitarget opioid ligands in pain relief: New players in an old game.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.00 | 9.00 |
| EC50 | 1 | 7.50 | 7.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL155892 | — | — | 1 | 9.00 |
| CHEMBL3759292 | — | — | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL155892 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3759292 | — | EC50 | = | 31.62 | nM | 7.50 |