Mu-type opioid receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt P97266. Use UniProt P97266 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P97266 as the stable identity anchor, then attach disease evidence before program review.
Mu-type opioid receptor
Review this target as Mu-type opioid receptor, mapped to UniProt P97266. Sequence length is 98 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mu-type opioid receptor as ChEMBL target CHEMBL4354, mapped to UniProt P97266. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Mu-type opioid receptor is the right protein anchor across sources, using UniProt P97266 as the stable mapping.
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| Preferred Name | Mu-type opioid receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | P97266 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mu-type opioid receptor |
| UniProt Accession | P97266 |
| Component Type | Protein |
| Sequence Length | 98 aa |
Mu-type opioid receptor
Review this target as Mu-type opioid receptor, mapped to UniProt P97266. Sequence length is 98 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2113675 | 11.0 | Ki | 0.01 | Preclinical |
| CHEMBL52451 | 10.89 | Ki | 0.013 | Preclinical |
| CHEMBL290429 | 10.72 | IC50 | 0.019 | Clinical |
| CHEMBL300662 | 10.68 | Ki | 0.021 | Preclinical |
| CHEMBL50594 | 10.59 | Ki | 0.026 | Preclinical |
| CHEMBL385759 | 10.57 | IC50 | 0.027 | Preclinical |
| CHEMBL56585 | 10.49 | Ki | 0.032 | Clinical |
| CHEMBL23362 | 10.47 | IC50 | 0.034 | Preclinical |
| CHEMBL51838 | 10.41 | Ki | 0.039 | Preclinical |
| CHEMBL150052 | 10.41 | Ki | 0.039 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 124 | 412 | 7.4 |
| cell membrane format | 99 | 321 | 7.9 |
| single protein format | 78 | 132 | 7.2 |
| assay format | 68 | 356 | 7.8 |
| cell-based format | 2 | 16 | 7.7 |
| organism-based format | 2 | 12 | 8.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 205 | 459 | 7.0 |
| assay format | 83 | 96 | 7.7 |
| cell membrane format | 26 | 15 | 6.6 |
| cell-based format | 3 | 11 | 6.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 2 | 8 | 6.7 |