Assay Detail
Functional
CHEMBL3767556
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Cytotoxicity against human HL60/ADR cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL60/ADR |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dispirocyclopropyldehydrocostus lactone selectively inhibits acute myelogenous leukemia cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.26 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 5.31 |
| CHEMBL88985 | DEHYDROCOSTUSLACTONE | — | 1 | 5.29 |
| CHEMBL3765076 | — | — | 1 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 4890.0 | nM | 5.31 |
| CHEMBL88985 | DEHYDROCOSTUSLACTONE | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL3765076 | — | IC50 | = | 6700.0 | nM | 5.17 |