Assay Detail
Functional
CHEMBL3768382
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against clinical isolates of Dengue virus 4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | dengue virus type 4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.90 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3763180 | — | — | 1 | 7.40 |
| CHEMBL3763981 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3763180 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3763981 | — | EC50 | = | 400.0 | nM | 6.40 |