Assay Detail
Functional
CHEMBL3768680
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Cytotoxicity against human NCI-H1299 cells assessed as reduction in cell viability after 48 hrs by MTT assay
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H1299 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Carbohydrate-based inducers of cellular stress for targeting cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.25 | 4.52 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3765259 | — | — | 1 | 4.52 |
| CHEMBL71595 | HYDROGEN PEROXIDE | 4.0 | 1 | 4.22 |
| CHEMBL3765134 | — | — | 1 | 4.12 |
| CHEMBL3765516 | — | — | 1 | 4.12 |
| CHEMBL1236821 | XYLOSE | 4.0 | 1 | - |
| CHEMBL3764021 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3765259 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL71595 | HYDROGEN PEROXIDE | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL3765134 | — | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL3765516 | — | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL1236821 | XYLOSE | Activity | - | — | - | |
| CHEMBL3764021 | — | Activity | - | — | - |