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Assay Detail

CHEMBL3769207

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Functional
Cytotoxicity against human colon cancer cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Cancer cell lines
Confidence 1 — Organism
Curated By Autocuration

Publication

3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins.
Karki SS, Das U, Umemura N, Sakagami H, Iwamoto S, Kawase M, Balzarini J, De Clercq E, Dimmock SG, Dimmock JR.
J Med Chem (2016) 59 : 763 -769
PubMed 26727215 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.90 5.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3763325 1 5.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3763325 IC50 = 1260.0 nM 5.90