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Assay Detail

CHEMBL3772102

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H] CGS 21680 from rat hippocampus adenosine A1 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Adenosine receptor A1 (CHEMBL318)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.
Donegan RK, Lieberman RL.
J Med Chem (2016) 59 : 788 -809
PubMed 26356532 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.89 8.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL45891 1 8.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL45891 Kd = 1.3 nM 8.89