Assay Detail
Binding
CHEMBL3772111
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at adenosine A3 receptor in human NPE cells assessed as inhibition of adenosine-triggered cell shrinkage
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transmembrane domain-containing protein TMIGD3 (CHEMBL3712907) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.72 | 7.72 |
| IC50 | 1 | 7.38 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111545 | — | — | 1 | 7.72 |
| CHEMBL344187 | — | — | 1 | 7.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111545 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL344187 | — | IC50 | = | 42.0 | nM | 7.38 |