Assay Detail
Functional
CHEMBL3773102
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Decrease in [14C]citrate uptake in iv dosed Wistar Han rat kidney measured after 185 to 200 mins by scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Feces |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3771118 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3771118 | — | IC50 | = | 1000.0 | nM | 6.00 |