Assay Detail
Binding
CHEMBL3777316
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of 2-[125I]Iodomelatonin from human MT2 melatonin receptor expressed in HEK cells after 120 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tactical Approaches to Interconverting GPCR Agonists and Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 10.50 | 10.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287560 | — | — | 1 | 10.70 |
| CHEMBL329263 | — | — | 1 | 10.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287560 | — | Ki | = | 0.02 | nM | 10.70 |
| CHEMBL329263 | — | Ki | = | 0.05 | nM | 10.30 |