Assay Detail
ADMET
CHEMBL3777697
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Cytotoxicity against mouse mutant BpRc1 cells after 48 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
In vivo phase II-enzymes inducers, as potential chemopreventive agents, based on the chalcone and furoxan skeletons.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.35 | 4.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3775744 | — | — | 1 | 4.42 |
| CHEMBL3775822 | — | — | 1 | 4.42 |
| CHEMBL242080 | E319 | — | 1 | 4.22 |
| CHEMBL294099 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3775744 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL3775822 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL242080 | E319 | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL294099 | — | IC50 | = | 150000.0 | nM | - |