Assay Detail
Binding
CHEMBL3778089
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full length recombinant human FLAG-tagged PCAF expressed in baculovirus infected Sf21 cells using N-terminal H3 peptide substrate after 10 mins by radiometric filter binding assay in presence of [3H]acetyl-CoA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf21 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33778 | ANACARDIC ACID | — | 1 | 5.30 |
| CHEMBL3774884 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33778 | ANACARDIC ACID | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3774884 | — | IC50 | = | 5000.0 | nM | 5.30 |