Assay Detail
Binding
CHEMBL3778090
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human PCAF catalytic domain (492 to 658 residues) using histone H3 peptide substrate after 1 hr by liquid scintillation counting method in presence of [3H]acetyl-CoA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.47 | 4.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33778 | ANACARDIC ACID | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33778 | ANACARDIC ACID | IC50 | = | 33900.0 | nM | 4.47 |