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Assay Detail

CHEMBL3783898

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Functional
Agonist activity at human CB2 receptor expressed in CHO cells after 30 mins by [35S]-GTPgammaS binding assay relative to control
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Identification of Novel GPR55 Modulators Using Cell-Impedance-Based Label-Free Technology.
Morales P, Whyte LS, Chicharro R, Gómez-Cañas M, Pazos MR, Goya P, Irving AJ, Fernández-Ruiz J, Ross RA, Jagerovic N.
J Med Chem (2016) 59 : 1840 -1853
PubMed 26789378 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Emax 1 - -
EC50 1 6.41 6.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3781953 2 6.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3781953 EC50 = 391.5 nM 6.41
CHEMBL3781953 Emax = 87.8 % -