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Assay Detail

CHEMBL3784258

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to thrombin (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prothrombin (CHEMBL204)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

On the enthalpic preference of fragment binding
Ferenczy GG, Keseru GM
Medchemcomm (2016) 7 : 332 -337
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 5.21 6.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1198148 1 6.96
CHEMBL20936 BENZAMIDINE 1 3.45

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1198148 Kd = 110.0 nM 6.96
CHEMBL20936 BENZAMIDINE Kd = 355000.0 nM 3.45