Assay Detail
ADMET
CHEMBL3784285
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Cytotoxic activity against mouse NIH/3T3 cells by SRB assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Converting maslinic acid into an effective inhibitor of acylcholinesterases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.78 | 4.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3086605 | — | — | 1 | 4.91 |
| CHEMBL3086609 | — | — | 1 | 4.89 |
| CHEMBL3086599 | — | — | 1 | 4.87 |
| CHEMBL3086612 | — | — | 1 | 4.85 |
| CHEMBL201515 | MASLINIC ACID | — | 1 | 4.78 |
| CHEMBL3781995 | — | — | 1 | 4.76 |
| CHEMBL3086604 | — | — | 1 | 4.67 |
| CHEMBL3086610 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3086605 | — | IC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL3086609 | — | IC50 | = | 12900.0 | nM | 4.89 |
| CHEMBL3086599 | — | IC50 | = | 13400.0 | nM | 4.87 |
| CHEMBL3086612 | — | IC50 | = | 14100.0 | nM | 4.85 |
| CHEMBL201515 | MASLINIC ACID | IC50 | = | 16600.0 | nM | 4.78 |
| CHEMBL3781995 | — | IC50 | = | 17300.0 | nM | 4.76 |
| CHEMBL3086604 | — | IC50 | = | 21600.0 | nM | 4.67 |
| CHEMBL3086610 | — | IC50 | = | 33100.0 | nM | 4.48 |