Assay Detail
Functional
CHEMBL3784409
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiferroptotic activity in human HT1080 cells assessed as inhibition of erastin-induced cell death
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-1080 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.22 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3633564 | — | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3633564 | — | IC50 | = | 6.0 | nM | 8.22 |