Assay Detail
Binding
CHEMBL3787927
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cell membranes
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of novel opioid ligands with a C-homomorphinan skeleton.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 8.85 | 10.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3785854 | — | — | 1 | 10.02 |
| CHEMBL3787263 | — | — | 1 | 9.52 |
| CHEMBL3787016 | — | — | 1 | 9.28 |
| CHEMBL3785265 | — | — | 1 | 9.23 |
| CHEMBL3786218 | — | — | 1 | 9.19 |
| CHEMBL3787663 | — | — | 1 | 8.64 |
| CHEMBL1797689 | — | — | 1 | 8.58 |
| CHEMBL3786970 | — | — | 1 | 8.56 |
| CHEMBL252172 | BNTX | — | 1 | 8.45 |
| CHEMBL3786083 | — | — | 1 | 8.01 |
| CHEMBL3786675 | — | — | 1 | 7.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3785854 | — | Ki | = | 0.0945 | nM | 10.02 |
| CHEMBL3787263 | — | Ki | = | 0.303 | nM | 9.52 |
| CHEMBL3787016 | — | Ki | = | 0.531 | nM | 9.28 |
| CHEMBL3785265 | — | Ki | = | 0.585 | nM | 9.23 |
| CHEMBL3786218 | — | Ki | = | 0.644 | nM | 9.19 |
| CHEMBL3787663 | — | Ki | = | 2.3 | nM | 8.64 |
| CHEMBL1797689 | — | Ki | = | 2.62 | nM | 8.58 |
| CHEMBL3786970 | — | Ki | = | 2.76 | nM | 8.56 |
| CHEMBL252172 | BNTX | Ki | = | 3.53 | nM | 8.45 |
| CHEMBL3786083 | — | Ki | = | 9.81 | nM | 8.01 |
| CHEMBL3786675 | — | Ki | = | 12.1 | nM | 7.92 |