Assay Detail
Functional
CHEMBL3789476
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Cytostatic activity against human CEM cells after 72 hrs by Coulter counter method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Exploring the purine core of 3'-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.44 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2094094 | — | — | 1 | 6.21 |
| CHEMBL3786405 | — | — | 1 | 4.66 |
| CHEMBL3786357 | — | — | 1 | - |
| CHEMBL3786058 | — | — | 1 | - |
| CHEMBL3787291 | — | — | 1 | - |
| CHEMBL3785697 | — | — | 1 | - |
| CHEMBL3785220 | — | — | 1 | - |
| CHEMBL3786547 | — | — | 1 | - |
| CHEMBL3785685 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2094094 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL3786405 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL3786357 | — | IC50 | > | 250000.0 | nM | - |
| CHEMBL3786058 | — | IC50 | = | 210000.0 | nM | - |
| CHEMBL3787291 | — | IC50 | = | 104000.0 | nM | - |
| CHEMBL3785697 | — | IC50 | >= | 250000.0 | nM | - |
| CHEMBL3785220 | — | IC50 | > | 250000.0 | nM | - |
| CHEMBL3786547 | — | IC50 | > | 250000.0 | nM | - |
| CHEMBL3785685 | — | IC50 | > | 250000.0 | nM | - |