Assay Detail
Functional
CHEMBL3789662
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A431 cells after 48 hrs by crystal violet staining based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-431 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.41 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3787074 | — | — | 1 | 6.47 |
| CHEMBL1096256 | AGELASTATIN A | — | 1 | 6.34 |
| CHEMBL3298663 | — | — | 1 | - |
| CHEMBL3787242 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3787074 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL1096256 | AGELASTATIN A | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL3298663 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL3787242 | — | IC50 | > | 1000.0 | nM | - |