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Assay Detail

CHEMBL3790692

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]deltrophine from human delta opioid receptor expressed in CHO-K1 cells after 120 mins by liquid scintillation counting method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO-K1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Delta-type opioid receptor (CHEMBL236)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Effects of polar receptor agonists designed for the periphery on ATP-induced Ca2+release from keratinocytes
Galla F, Bourgeois C, Lehmkuhl K, Schepmann D, Soeberdt M, Lotts T, Abels C, Stander S, Wunsch B
Medchemcomm (2016) 7 : 317 -326
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.96 8.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL13470 SNC-80 1 8.92
CHEMBL80 NALOXONE 4.0 1 6.99

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL13470 SNC-80 Ki = 1.2 nM 8.92
CHEMBL80 NALOXONE Ki = 103.0 nM 6.99