Assay Detail
Functional
CHEMBL3800867
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Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and evaluation of novel oxadiazole derivatives as potential prostate cancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.65 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 7.52 |
| CHEMBL3799037 | — | — | 1 | 5.88 |
| CHEMBL3799243 | — | — | 1 | 5.60 |
| CHEMBL3800522 | — | — | 1 | 5.50 |
| CHEMBL3799206 | — | — | 1 | 5.41 |
| CHEMBL3800551 | — | — | 1 | 5.18 |
| CHEMBL3800452 | — | — | 1 | 4.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185 | FLUOROURACIL | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL3799037 | — | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL3799243 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL3800522 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL3799206 | — | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL3800551 | — | IC50 | = | 6550.0 | nM | 5.18 |
| CHEMBL3800452 | — | IC50 | = | 32330.0 | nM | 4.49 |