Assay Detail
Functional
CHEMBL3800883
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Cytotoxicity against mouse L5178Y cells assessed as growth inhibition after 72 hrs by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L5178Y |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of selenocompounds with promising properties to reverse cancer multidrug resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.51 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3122193 | — | — | 1 | 6.11 |
| CHEMBL3122194 | — | — | 1 | 6.03 |
| CHEMBL3122195 | — | — | 1 | 5.88 |
| CHEMBL3122177 | — | — | 1 | 5.40 |
| CHEMBL479 | THIORIDAZINE | 4.0 | 1 | 4.90 |
| CHEMBL3122202 | — | — | 1 | 4.71 |
| CHEMBL3122203 | — | — | 1 | - |
| CHEMBL3122201 | — | — | 1 | - |
| CHEMBL3122200 | — | — | 1 | - |
| CHEMBL3122173 | — | — | 1 | - |
| CHEMBL3122179 | — | — | 1 | - |
| CHEMBL3122190 | — | — | 1 | - |
| CHEMBL6966 | VERAPAMIL | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3122193 | — | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL3122194 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL3122195 | — | IC50 | = | 1310.0 | nM | 5.88 |
| CHEMBL3122177 | — | IC50 | = | 3970.0 | nM | 5.40 |
| CHEMBL479 | THIORIDAZINE | IC50 | = | 12720.0 | nM | 4.90 |
| CHEMBL3122202 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL3122203 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3122201 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3122200 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3122173 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3122179 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3122190 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL6966 | VERAPAMIL | IC50 | > | 100000.0 | nM | - |