Assay Detail
Binding
CHEMBL3801006
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Binding affinity to human recombinant CA7 after 30 secs by surface plasmon resonance assay
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 16 | 6.97 | 8.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2333418 | — | — | 1 | 8.19 |
| CHEMBL3797385 | — | — | 1 | 8.17 |
| CHEMBL2011156 | — | — | 1 | 8.11 |
| CHEMBL2443188 | — | — | 1 | 7.92 |
| CHEMBL3798446 | — | — | 1 | 7.77 |
| CHEMBL3797893 | — | — | 1 | 7.57 |
| CHEMBL3798303 | — | — | 1 | 7.40 |
| CHEMBL3799577 | — | — | 1 | 7.35 |
| CHEMBL2010994 | — | — | 1 | 7.29 |
| CHEMBL1272242 | — | — | 1 | 6.51 |
| CHEMBL2011155 | — | — | 1 | 6.43 |
| CHEMBL3797835 | — | — | 1 | 6.29 |
| CHEMBL3799296 | — | — | 1 | 5.82 |
| CHEMBL1272187 | — | — | 1 | 5.77 |
| CHEMBL2443189 | — | — | 1 | 5.66 |
| CHEMBL3799945 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2333418 | — | Kd | = | 6.5 | nM | 8.19 |
| CHEMBL3797385 | — | Kd | = | 6.8 | nM | 8.17 |
| CHEMBL2011156 | — | Kd | = | 7.7 | nM | 8.11 |
| CHEMBL2443188 | — | Kd | = | 12.0 | nM | 7.92 |
| CHEMBL3798446 | — | Kd | = | 17.0 | nM | 7.77 |
| CHEMBL3797893 | — | Kd | = | 27.0 | nM | 7.57 |
| CHEMBL3798303 | — | Kd | = | 40.0 | nM | 7.40 |
| CHEMBL3799577 | — | Kd | = | 45.0 | nM | 7.35 |
| CHEMBL2010994 | — | Kd | = | 51.0 | nM | 7.29 |
| CHEMBL1272242 | — | Kd | = | 310.0 | nM | 6.51 |
| CHEMBL2011155 | — | Kd | = | 370.0 | nM | 6.43 |
| CHEMBL3797835 | — | Kd | = | 510.0 | nM | 6.29 |
| CHEMBL3799296 | — | Kd | = | 1500.0 | nM | 5.82 |
| CHEMBL1272187 | — | Kd | = | 1700.0 | nM | 5.77 |
| CHEMBL2443189 | — | Kd | = | 2200.0 | nM | 5.66 |
| CHEMBL3799945 | — | Kd | = | 4800.0 | nM | 5.32 |