Assay Detail
Binding
CHEMBL3801100
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Inhibition of ABL (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A multicomponent pharmacophore fragment-decoration approach to identify selective LRRK2-targeting probes
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.45 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL288441 | BOSUTINIB | 4.0 | 1 | 10.00 |
| CHEMBL1336 | SORAFENIB | 4.0 | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL288441 | BOSUTINIB | Kd | = | 0.1 | nM | 10.00 |
| CHEMBL1336 | SORAFENIB | Kd | = | 130.0 | nM | 6.89 |