Assay Detail
Functional
CHEMBL3801721
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Cytotoxicity against human NCI-H929 cells after 48 hrs by MTS assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H929 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dysiherbols A-C and Dysideanone E, Cytotoxic and NF-κB Inhibitory Tetracyclic Meroterpenes from a Dysidea sp. Marine Sponge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.25 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3798375 | — | — | 1 | 6.24 |
| CHEMBL459814 | AVAROL | — | 1 | 5.48 |
| CHEMBL438139 | ROCAGLAMIDE | — | 1 | 5.41 |
| CHEMBL3800586 | — | — | 1 | 4.92 |
| CHEMBL3798054 | — | — | 1 | 4.82 |
| CHEMBL3800631 | — | — | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3798375 | — | IC50 | = | 580.0 | nM | 6.24 |
| CHEMBL459814 | AVAROL | IC50 | = | 3320.0 | nM | 5.48 |
| CHEMBL438139 | ROCAGLAMIDE | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL3800586 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL3798054 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL3800631 | — | IC50 | = | 25000.0 | nM | 4.60 |