Assay Detail
Binding
CHEMBL3802097
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Inhibition of DAPK2 (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.19 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3799389 | — | — | 1 | 6.77 |
| CHEMBL3797466 | — | — | 1 | 6.24 |
| CHEMBL3799585 | — | — | 1 | 6.23 |
| CHEMBL513703 | — | — | 1 | 6.08 |
| CHEMBL3797480 | — | — | 1 | 5.64 |
| CHEMBL3799505 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3799389 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL3797466 | — | IC50 | = | 570.0 | nM | 6.24 |
| CHEMBL3799585 | — | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL513703 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL3797480 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL3799505 | — | IC50 | > | 10000.0 | nM | - |