Assay Detail
Binding
CHEMBL3808043
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human estrone sulfatase using 4-methylumbelliferyl sulfate as substrate by colorimetric assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 9.47 | 9.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL262050 | — | — | 1 | 9.47 |
| CHEMBL361700 | — | — | 1 | - |
| CHEMBL188214 | — | — | 1 | - |
| CHEMBL361924 | — | — | 1 | - |
| CHEMBL188128 | — | — | 1 | - |
| CHEMBL183996 | — | — | 1 | - |
| CHEMBL185877 | — | — | 1 | - |
| CHEMBL189863 | — | — | 1 | - |
| CHEMBL364624 | — | — | 1 | - |
| CHEMBL184540 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL262050 | — | IC50 | = | 0.34 | nM | 9.47 |
| CHEMBL361700 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL188214 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL361924 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL188128 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL183996 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL185877 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL189863 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL364624 | — | IC50 | > | 530.0 | nM | - |
| CHEMBL184540 | — | IC50 | > | 530.0 | nM | - |