Assay Detail
Functional
CHEMBL3810633
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.95 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5316205 | — | — | 1 | 5.09 |
| CHEMBL611368 | LICOCOUMARONE | — | 1 | 5.07 |
| CHEMBL3810225 | — | — | 1 | 4.92 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5316205 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL611368 | LICOCOUMARONE | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL3810225 | — | IC50 | = | 12100.0 | nM | 4.92 |
| CHEMBL140 | CURCUMIN | IC50 | = | 19100.0 | nM | 4.72 |