Assay Detail
Functional
CHEMBL3810643
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTS assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.12 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL481 | IRINOTECAN | 4.0 | 1 | 6.10 |
| CHEMBL3809403 | — | — | 1 | 5.19 |
| CHEMBL1929043 | LICORICIDIN | — | 1 | 5.16 |
| CHEMBL3808919 | — | — | 1 | 5.15 |
| CHEMBL1563332 | GLYASPERIN D | — | 1 | 4.89 |
| CHEMBL3809552 | — | — | 1 | 4.69 |
| CHEMBL3810179 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL481 | IRINOTECAN | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL3809403 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL1929043 | LICORICIDIN | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL3808919 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL1563332 | GLYASPERIN D | IC50 | = | 12900.0 | nM | 4.89 |
| CHEMBL3809552 | — | IC50 | = | 20300.0 | nM | 4.69 |
| CHEMBL3810179 | — | IC50 | = | 23100.0 | nM | 4.64 |