Assay Detail
Binding
CHEMBL3810646
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.73 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3808919 | — | — | 1 | 6.40 |
| CHEMBL3809403 | — | — | 1 | 5.52 |
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3808919 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL3809403 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL169 | URSOLIC ACID | IC50 | = | 5200.0 | nM | 5.28 |