Assay Detail
Binding
CHEMBL3810649
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate assessed as oxidation of L-tyrosine after 15 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.52 | 6.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1563332 | GLYASPERIN D | — | 1 | 6.81 |
| CHEMBL1630857 | GLYASPERIN C | — | 1 | 6.75 |
| CHEMBL150 | KAEMPFEROL | 1.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1563332 | GLYASPERIN D | IC50 | = | 154.0 | nM | 6.81 |
| CHEMBL1630857 | GLYASPERIN C | IC50 | = | 177.0 | nM | 6.75 |
| CHEMBL150 | KAEMPFEROL | IC50 | = | 1000.0 | nM | 6.00 |