Assay Detail
Binding
CHEMBL3811620
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Inhibition of purified human factor 11a after 30 to 60 mins
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Atropisomer Control in Macrocyclic Factor VIIa Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.08 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3809472 | — | — | 1 | 5.24 |
| CHEMBL3808399 | — | — | 1 | 5.04 |
| CHEMBL3808853 | — | — | 1 | 4.97 |
| CHEMBL3809352 | — | — | 1 | - |
| CHEMBL3809344 | — | — | 1 | - |
| CHEMBL3809993 | — | — | 1 | - |
| CHEMBL3809909 | — | — | 1 | - |
| CHEMBL3808801 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3809472 | — | Ki | = | 5700.0 | nM | 5.24 |
| CHEMBL3808399 | — | Ki | = | 9100.0 | nM | 5.04 |
| CHEMBL3808853 | — | Ki | = | 10800.0 | nM | 4.97 |
| CHEMBL3809352 | — | Ki | > | 11000.0 | nM | - |
| CHEMBL3809344 | — | Ki | > | 14200.0 | nM | - |
| CHEMBL3809993 | — | Ki | > | 14200.0 | nM | - |
| CHEMBL3809909 | — | Ki | > | 14200.0 | nM | - |
| CHEMBL3808801 | — | Ki | > | 14200.0 | nM | - |