Assay Detail
Functional
CHEMBL3812489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human KMS-12-BM cells after 72 hrs by cell titer-glo luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KMS-12-BM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.82 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3809691 | — | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3809691 | — | IC50 | = | 151.0 | nM | 6.82 |