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Assay Detail

CHEMBL3816136

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Functional
Antiviral activity against human rhinovirus 17 assessed as reduction in viral infection in human HeLa H1 cells after 2 to 5 days by XTT reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human rhinovirus B17
Cell Type HeLa H1
Confidence 1 — Organism
Curated By Autocuration

Publication

Design and structure-activity relationships of novel inhibitors of human rhinovirus 3C protease.
Kawatkar SP, Gagnon M, Hoesch V, Tiong-Yip C, Johnson K, Ek M, Nilsson E, Lister T, Olsson L, Patel J, Yu Q.
Bioorg Med Chem Lett (2016) 26 : 3248 -3252
PubMed 27265257 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.85 7.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL20210 RUPINTRIVIR 2.0 1 7.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL20210 RUPINTRIVIR EC50 = 14.0 nM 7.85