Assay Detail
Functional
CHEMBL3816997
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human G122 cells after 4 days by CellTitre-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | G122 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3813842 | PAXALISIB | 2.0 | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3813842 | PAXALISIB | EC50 | = | 1010.0 | nM | 6.00 |