Assay Detail
Binding
CHEMBL3819920
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of TCPTP (unknown origin) by UV/Vis spectrophotometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 2 (CHEMBL3807) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The design strategy of selective PTP1B inhibitors over TCPTP.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.98 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269166 | — | — | 1 | 8.52 |
| CHEMBL266753 | — | — | 1 | 7.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269166 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL266753 | — | IC50 | = | 36.0 | nM | 7.44 |