Assay Detail
Functional
CHEMBL3820980
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.09 | 8.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2386353 | — | — | 1 | 8.23 |
| CHEMBL1829174 | FASIGLIFAM | 3.0 | 1 | 7.24 |
| CHEMBL1829173 | — | — | 1 | 6.77 |
| CHEMBL108766 | DODECANOATE | — | 1 | 6.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2386353 | — | EC50 | = | 5.888 | nM | 8.23 |
| CHEMBL1829174 | FASIGLIFAM | EC50 | = | 57.54 | nM | 7.24 |
| CHEMBL1829173 | — | EC50 | = | 169.82 | nM | 6.77 |
| CHEMBL108766 | DODECANOATE | EC50 | = | 758.58 | nM | 6.12 |