Assay Detail
Functional
CHEMBL3821428
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Antiproliferative activity against mouse MAC16 cells assessed as reduction in cell viability after 3 days by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | MAC16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cholecystokinin-1 receptor antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anticancer agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.66 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3818164 | — | — | 1 | 7.12 |
| CHEMBL3818718 | — | — | 1 | 7.07 |
| CHEMBL3818215 | — | — | 1 | 7.02 |
| CHEMBL1255589 | LORGLUMIDE SODIUM | — | 1 | 6.07 |
| CHEMBL39263 | — | — | 1 | 6.00 |
| CHEMBL3818410 | — | — | 1 | - |
| CHEMBL9387 | L-365260 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3818164 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL3818718 | — | IC50 | = | 86.0 | nM | 7.07 |
| CHEMBL3818215 | — | IC50 | = | 96.0 | nM | 7.02 |
| CHEMBL1255589 | LORGLUMIDE SODIUM | IC50 | = | 861.0 | nM | 6.07 |
| CHEMBL39263 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3818410 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL9387 | L-365260 | IC50 | > | 5000.0 | nM | - |