Assay Detail
Functional
CHEMBL3821471
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Antiproliferative activity against human IGROV1 cells assessed as cell growth inhibition after 24 hrs by coulter counter method
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | IGROV-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthetic sulfoglycolipids targeting the serine-threonine protein kinase Akt.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.11 | 6.52 |
| GI | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3819449 | — | — | 1 | 6.52 |
| CHEMBL3818018 | — | — | 1 | 5.70 |
| CHEMBL3819502 | — | — | 1 | - |
| CHEMBL3818066 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3819449 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL3818018 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL3819502 | — | GI | - | — | - | |
| CHEMBL3818066 | — | GI | - | — | - |