Assay Detail
Binding
CHEMBL3824486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at rat GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glucagon-like peptide 2 receptor (CHEMBL3822349) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Synthesis and Pharmacological Characterization of Novel Glucagon-like Peptide-2 (GLP-2) Analogues with Low Systemic Clearance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 10.25 | 10.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3823541 | — | — | 1 | 10.40 |
| CHEMBL2104987 | TEDUGLUTIDE | 4.0 | 1 | 10.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3823541 | — | EC50 | = | 0.04 | nM | 10.40 |
| CHEMBL2104987 | TEDUGLUTIDE | EC50 | = | 0.08 | nM | 10.10 |