Assay Detail
Functional
CHEMBL3824701
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human SK-MEL-188 cells measured after 48 hrs by MTS/PMS assay
10
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and Biological Evaluation of Vitamin D3 Metabolite 20S,23S-Dihydroxyvitamin D3 and Its 23R Epimer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| GI | 5 | - | - |
| IC50 | 5 | 11.00 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3823776 | — | — | 2 | 11.00 |
| CHEMBL3824029 | — | — | 2 | 11.00 |
| CHEMBL3822832 | — | — | 2 | 11.00 |
| CHEMBL3822994 | — | — | 2 | 11.00 |
| CHEMBL846 | CALCITRIOL | 4.0 | 2 | 11.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3823776 | — | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL3824029 | — | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL3822832 | — | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL3822994 | — | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL846 | CALCITRIOL | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL3823776 | — | GI | - | — | - | |
| CHEMBL3824029 | — | GI | - | — | - | |
| CHEMBL3822832 | — | GI | - | — | - | |
| CHEMBL3822994 | — | GI | - | — | - | |
| CHEMBL846 | CALCITRIOL | GI | - | — | - |