Assay Detail
Binding
CHEMBL3824787
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CK2alpha (2 to 391 residues) using [33P]-ATP by scintillation counting based radioactive filter binding assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Enriching screening libraries with bioactive fragment space.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 5.11 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2087023 | — | — | 1 | 7.70 |
| CHEMBL3823403 | — | — | 1 | 6.28 |
| CHEMBL3824310 | — | — | 1 | 4.96 |
| CHEMBL3823253 | — | — | 1 | 4.94 |
| CHEMBL3823241 | — | — | 1 | 4.82 |
| CHEMBL3824125 | — | — | 1 | 4.79 |
| CHEMBL3823073 | — | — | 1 | 4.77 |
| CHEMBL3823802 | — | — | 1 | 4.70 |
| CHEMBL3823680 | — | — | 1 | 4.10 |
| CHEMBL3823185 | — | — | 1 | 3.99 |
| CHEMBL3823658 | — | — | 1 | - |
| CHEMBL3823750 | — | — | 1 | - |
| CHEMBL3823560 | — | — | 1 | - |
| CHEMBL3822582 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2087023 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3823403 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL3824310 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL3823253 | — | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL3823241 | — | IC50 | = | 15200.0 | nM | 4.82 |
| CHEMBL3824125 | — | IC50 | = | 16100.0 | nM | 4.79 |
| CHEMBL3823073 | — | IC50 | = | 16900.0 | nM | 4.77 |
| CHEMBL3823802 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL3823680 | — | IC50 | = | 79300.0 | nM | 4.10 |
| CHEMBL3823185 | — | IC50 | = | 102600.0 | nM | 3.99 |
| CHEMBL3823658 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL3823750 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL3823560 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL3822582 | — | IC50 | > | 200000.0 | nM | - |