Compound Detail
CHEMBL3823073
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Basic Information
| ChEMBL ID | CHEMBL3823073 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FJBHFPRURAMZGR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
294.3
MW (Da)
1.84
ALogP
3
HBA
3
HBD
100.9
PSA (Ų)
0.68
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Casein kinase II subunit alpha CHEMBL3629 | IC50 | 4.77 | 4.77 | 16900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Casein kinase II subunit alpha | IC50 | = | 16900.0 | nM | 4.77 | Inhibition of human CK2alpha (2 to 391 residues) using [33P]-ATP by scintillatio... | 27311891 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27311891 | 10.1016/j.bmcl.2016.06.013 | Casein kinase II subunit alpha | 1 |
Data from ChEMBL 36 via Core Engine