Assay Detail
Binding
CHEMBL3826757
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from mu-type opioid receptor in rat brain membranes incubated for 2 hrs
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
[Dmt(1)]DALDA analogues modified with tyrosine analogues at position 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 9.14 | 9.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2181202 | — | — | 1 | 9.85 |
| CHEMBL3822676 | — | — | 1 | 9.44 |
| CHEMBL3823054 | — | — | 1 | 9.34 |
| CHEMBL3822822 | — | — | 1 | 9.06 |
| CHEMBL60444 | — | — | 1 | 8.77 |
| CHEMBL3822702 | — | — | 1 | 8.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2181202 | — | Ki | = | 0.143 | nM | 9.85 |
| CHEMBL3822676 | — | Ki | = | 0.367 | nM | 9.44 |
| CHEMBL3823054 | — | Ki | = | 0.458 | nM | 9.34 |
| CHEMBL3822822 | — | Ki | = | 0.875 | nM | 9.06 |
| CHEMBL60444 | — | Ki | = | 1.69 | nM | 8.77 |
| CHEMBL3822702 | — | Ki | = | 4.29 | nM | 8.37 |