Assay Detail
Toxicity
CHEMBL3854541
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Cytotoxicity against African green monkey Vero cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.18 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | — | 1 | 6.00 |
| CHEMBL503 | LOVASTATIN | 4.0 | 1 | 5.66 |
| CHEMBL3946905 | — | — | 1 | 5.09 |
| CHEMBL3916495 | — | — | 1 | 5.08 |
| CHEMBL3978069 | — | — | 1 | 4.84 |
| CHEMBL3986260 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL503 | LOVASTATIN | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL3946905 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL3916495 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL3978069 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL3986260 | — | IC50 | = | 40000.0 | nM | 4.40 |