Assay Detail
Functional
CHEMBL3854698
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antithrombotic activity in iv dosed New Zealand White rabbit electrically-induced carotid artery thrombosis model assessed as reduction in thrombus formation
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.44 | 6.44 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3902498 | — | — | 2 | 6.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3902498 | — | EC50 | = | 360.0 | nM | 6.44 |
| CHEMBL3902498 | — | Activity | - | — | - |